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Background and Aim: Nurses engage in most duties related to clients' treatment and recovery. Performing nursing care with high quality results patient satisfaction and help them for self-care. So this study conducted to determine the patient satisfaction of nursing care in medical-surgical wards of Birjand hospitals.   Materials and Methods: In This descriptive study, 300 patients discharged from medical-surgical wards in research period by purposeful sampling. Patients were interviewed from 2 hours before discharging. Patient satisfaction of 5 roles of nurses were assessed by 3 item Likert scale   Results: In total score patients27.2% highly, 66% moderately and 6.8% mildly were satisfied. P.S. of different roles of nursing was: treatment role 11.6% mild, 48.8% moderate and 39.6% high communication 5.2% mild, 52% moderate and 42.8% high management 28% mild, 61.2% moderate and 10.8% high educational role 27.2% mild, 58% moderate and 14.8% high and protective 21.2% mild, 53.6% moderate and 25.2% high. There was significant relationship between P.S. and age, sex, marital status, ward, job and type of insurance variables.   Conclusion: Decreasing unnecessary works of nurses, increasing communication between client and nurse, and continuous education of nurses, make positive attitude toward nursing and reflecting to community, decrease hospitalization period and treatment costs.

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