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Improvement in communication with patients can improve assessment and identifying patients' problems by promotion the interaction and active listening. This study was done to determine effective factors and barriers in communication with patients from nurses' perspective.   Materials and MethodsIn this descriptive-analytic study, 70 nurses working in Val-e-Asr hospital were selected randomly. Data was collected by 28 options questionnaire about effective factors & barriers. It is designed in 6 domainsnurse, patient, nurse-patient, environment, knowledge and skill and working condition. Data were analyzed by SPSS software, descriptive statistics and c 2 test.   ResultsThe most effective factors in communication with patients are nurse factors (84.3%), knowledge & skill (75.7%) and patient’s factors (74.3%). The most effective barriers are nurses factors and knowledge & skill (75.7%) and environment (70%). There is significant relationship between sex and nurses factors (P=0.38) and in effective barriers there is relationship and working conditions (P=0.27, P=0.08).   ConclusionAccording to results, most effective factors are nurses, knowledge & skill so nurses, educational needs are important and it is recommended to plan for reliefing nurses, clinical problems and providing better care.

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