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Volume 7, Issue 2 (9-2010)
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Alizadeh A M, Rostamian A, Saeedpour K, Hemmati M, Khorasani Z, Mohagheghi M A, et al . Drug interactions frequency in the bedridden patients in three hospitals of Tehran city. Mod Care J 2010; 7 (2) :22-27
URL: http://mcj.bums.ac.ir/article-1-357-en.html
URL: http://mcj.bums.ac.ir/article-1-357-en.html
Ali Mohammad Alizadeh *1 
, Abdurrhman Rostamian2 , Khadijeh Saeedpour3 , Mohammad Hemmati4 , Zahra Khorasani3 , Mohammad Ali Mohagheghi5 , Minoo Khatami Moghaddam6 , Maryam Alsadat Mousavi3
, Abdurrhman Rostamian2 , Khadijeh Saeedpour3 , Mohammad Hemmati4 , Zahra Khorasani3 , Mohammad Ali Mohagheghi5 , Minoo Khatami Moghaddam6 , Maryam Alsadat Mousavi3
1- PhD of Physiology, Cancer Research Center, Cancer Institute, Tehran University of Medical Sciences, Tehran, Iran. Email: aalizadeh@razi.tums.ac.ir
2- Assistant Professor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3- Nurse, Tehran University of Medical Sciences, Tehran, Iran
4- PhD Student, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
5- Associate Professor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
6- Pharmacist, Instructor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2- Assistant Professor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
3- Nurse, Tehran University of Medical Sciences, Tehran, Iran
4- PhD Student, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
5- Associate Professor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
6- Pharmacist, Instructor, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Abstract: (213 Views)
Background and Aim: Drug interaction includes the effect of a drug, food or anything that can induce changes in the pharmacokinetic or pharmacodynamic properties of a certain drug. The aim of the present study is to assess drug interactions of bedridden patients in three Tehran hospitals. Materials and Methods: This retrospective research was accomplished on 400 bedridden patient’s dossiers in three hospitals of Tehran city at secondary half of 2006 year . Questionnaire was used according to Hansten classifications to gather information from available data. Results: Dossiers assessment showed 1087 visits and 2610 drug order. 168 dossiers (42%) were found having drug-drug interactions (568 cases). Drug interactions were severe (4.4%), moderate (47%) and mild (48.6%). Antibiotics had the commonest (27.5%), while the neuroleptics and digitalis (0.5%) and bronchodilators (0.3%) brought about the least drug interactions. Conclusion: Our findings showed that the drug prescription doesn't follow a correct logic and is still increasing in comparison to the past.
Article Types: Research Article |
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Received: 2026/01/25 | Accepted: 2026/01/27 | Published: 2026/01/27
Received: 2026/01/25 | Accepted: 2026/01/27 | Published: 2026/01/27
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