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Volume 20, Issue 4 (10-2023)
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Mortazavi Y, Amri P, Khosravi Larijani A, Mohebbisamimi K, Esbakian B, Hasan Jafarpoor H. Effects of Parenteral Nutrition with Amino Acid Alone and Amino Acid-Intralipid Combination on Vital Signs and Rate of Diuresis in ICU Patients. Mod Care J 2023; 20 (4) : e137649
URL: http://mcj.bums.ac.ir/article-1-282-en.html
URL: http://mcj.bums.ac.ir/article-1-282-en.html
Yousef Mortazavi1 
, Parviz Amri2 , Alireza Khosravi Larijani3 , Katayoun Mohebbisamimi3 , Behnam Esbakian1 , Hasanali Hasan Jafarpoor *4
, Parviz Amri2 , Alireza Khosravi Larijani3 , Katayoun Mohebbisamimi3 , Behnam Esbakian1 , Hasanali Hasan Jafarpoor *4
1- Department of Anesthesiology and Operating Room, School of Allied Medical Sciences, Babol University of Medical Sciences, Babol, Iran
2- Department of Anesthesiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
3- Student Research Committee, Nursing Care Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
4- Department of Anesthesiology and Operating Room, School of Allied Medical Sciences and Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran ,jafarpoor_hasan@yahoo.com
2- Department of Anesthesiology, School of Medicine, Babol University of Medical Sciences, Babol, Iran
3- Student Research Committee, Nursing Care Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
4- Department of Anesthesiology and Operating Room, School of Allied Medical Sciences and Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran ,
Abstract: (161 Views)
Background: Nearly all cases admitted to intensive care units (ICUs) suffer from poor nutritional status. Accordingly, the type of parenteral nutrition administered can influence these patients’ health conditions.
Objectives: This study aimed to compare the effects of parenteral nutrition with the amino acid alone and amino acid-intralipid combination on vital signs and rate of diuresis in ICU patients.
Methods: This prospective cohort study was conducted over two years, from March 2021 to March 2023. Patients under intravenous nutrition with amino acid (Group A) and amino acid-intralipid (Group B) for three days (as ordered by the ICU specialist) were examined. The patients' vital signs and laboratory findings were recorded before and after the nutrition. The data were analyzed using SPSS v. 26.
Results: The patients were homogeneous regarding age, sex, disease history, and diagnosis (P < 0.05). After parenteral feeding, urine and blood urea nitrogen/creatinine ratio respectively increased and decreased in Group B. Moreover, the serum bilirubin level significantly decreased in Group B, and SGOT and SGPT increased in Group A. In addition, the breathing rate significantly increased in Group A after intravenous feeding (P < 0.001).
Conclusions: Although intravenous amino acid-intralipid nutrition increased and decreased urine and blood urea nitrogen/creatinine, respectively, the patients who received amino acid alone also experienced an increase in urine volume and respiratory rate. Therefore, intravenous amino acid nutrition alone can be cost-effective.
Objectives: This study aimed to compare the effects of parenteral nutrition with the amino acid alone and amino acid-intralipid combination on vital signs and rate of diuresis in ICU patients.
Methods: This prospective cohort study was conducted over two years, from March 2021 to March 2023. Patients under intravenous nutrition with amino acid (Group A) and amino acid-intralipid (Group B) for three days (as ordered by the ICU specialist) were examined. The patients' vital signs and laboratory findings were recorded before and after the nutrition. The data were analyzed using SPSS v. 26.
Results: The patients were homogeneous regarding age, sex, disease history, and diagnosis (P < 0.05). After parenteral feeding, urine and blood urea nitrogen/creatinine ratio respectively increased and decreased in Group B. Moreover, the serum bilirubin level significantly decreased in Group B, and SGOT and SGPT increased in Group A. In addition, the breathing rate significantly increased in Group A after intravenous feeding (P < 0.001).
Conclusions: Although intravenous amino acid-intralipid nutrition increased and decreased urine and blood urea nitrogen/creatinine, respectively, the patients who received amino acid alone also experienced an increase in urine volume and respiratory rate. Therefore, intravenous amino acid nutrition alone can be cost-effective.
Article number: e137649
Article Types: Research Article |
Subject:
General
Received: 2023/05/20 | Accepted: 2023/08/9 | Published: 2023/10/15
Received: 2023/05/20 | Accepted: 2023/08/9 | Published: 2023/10/15
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