Modern Care Journal
Sun, Aug 2, 2026
[Archive]
Volume 20, Issue 4 (10-2023)
|
Back to browse issues page
Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:
Parvaie P, Mousavi-nejad S F, Atabati E. The Impact of an Oral Hygiene Education Module on Inflammatory Factors in Patients with Active Systemic Lupus Erythematosus. Mod Care J 2023; 20 (4) : e136708
URL: http://mcj.bums.ac.ir/article-1-277-en.html
URL: http://mcj.bums.ac.ir/article-1-277-en.html
1- Department of Oral & Maxillofacial Diseases, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran , parvin.parvaie@yahoo.com
2- Dental Clinical Research Development Unit, Birjand University of Medical Sciences, Birjand, Iran
3- Clinical Research Development Unit, Birjand University of Medical Sciences, Birjand, Iran
2- Dental Clinical Research Development Unit, Birjand University of Medical Sciences, Birjand, Iran
3- Clinical Research Development Unit, Birjand University of Medical Sciences, Birjand, Iran
Abstract: (150 Views)
Background: In patients with active systemic lupus erythematosus (SLE), inflammatory markers such as erythrocyte sedimentation rate (ESR) and serum C-reactive protein (CRP) are often elevated. Increases in these inflammatory biomarkers have been linked to periodontal diseases.
Objectives: This study aimed to investigate the impact of oral health education on inflammatory markers in patients with SLE.
Methods: In this field trial study, 40 SLE patients with no dental plaque were assigned to the intervention and control groups by block randomization design. The intervention group was educated in a 20-minute session based on Bass’s method of tooth brushing. Before and 3 months after the intervention, the dental plaque, CRP, ESR, and double-stranded DNA (anti-dsDNA) levels were determined in the two groups. Data were analyzed with SPSS software using independent t-test, Wilcoxon, Mann-Whitney, and univariate covariance analysis at 0.05 significance level.
Results: In terms of basic variables, there was no significant difference between the two groups. O’Leary’s plaque index in the intervention group showed a significant decrease over time, but no significant reduction was observed in the control group. The difference between the two groups was statistically significant (P < 0.001). The results of covariance analysis and controlling for the effect on patients' performance showed that the health education intervention had a significant impact on ESR (effect size = 9.6%). However, the intervention had a slight effect on CRP, dsDNA, and SLE Disease Activity Index (SLE-DAI). Moreover, CRP, ESR, and dsDNA showed a significant decrease in both groups after the intervention; however, the difference was not significant.
Conclusions: According to the results of the study, it is recommended to implement educational programs in the field of oral and dental hygiene and the correct way of brushing teeth for patients with SLE.
Objectives: This study aimed to investigate the impact of oral health education on inflammatory markers in patients with SLE.
Methods: In this field trial study, 40 SLE patients with no dental plaque were assigned to the intervention and control groups by block randomization design. The intervention group was educated in a 20-minute session based on Bass’s method of tooth brushing. Before and 3 months after the intervention, the dental plaque, CRP, ESR, and double-stranded DNA (anti-dsDNA) levels were determined in the two groups. Data were analyzed with SPSS software using independent t-test, Wilcoxon, Mann-Whitney, and univariate covariance analysis at 0.05 significance level.
Results: In terms of basic variables, there was no significant difference between the two groups. O’Leary’s plaque index in the intervention group showed a significant decrease over time, but no significant reduction was observed in the control group. The difference between the two groups was statistically significant (P < 0.001). The results of covariance analysis and controlling for the effect on patients' performance showed that the health education intervention had a significant impact on ESR (effect size = 9.6%). However, the intervention had a slight effect on CRP, dsDNA, and SLE Disease Activity Index (SLE-DAI). Moreover, CRP, ESR, and dsDNA showed a significant decrease in both groups after the intervention; however, the difference was not significant.
Conclusions: According to the results of the study, it is recommended to implement educational programs in the field of oral and dental hygiene and the correct way of brushing teeth for patients with SLE.
Article number: e136708
Article Types: Research Article |
Subject:
General
Received: 2023/04/10 | Accepted: 2023/05/21 | Published: 2023/10/15
Received: 2023/04/10 | Accepted: 2023/05/21 | Published: 2023/10/15
Send email to the article author
| Rights and permissions | |
 |
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. |
