fa بررسی تأثیر کپسول زینتوما (زنجبیل) بر شدّت درد قاعدگی دردناک اولیه General پژوهشي Research Article Background and AimTo determine whether Zintoma (Ginger) is effective in the treatment of primary dysmenorrhoea. Materials and MethodsIn this double-blind, cross-over study 66 students, who suffered from primary dysmenorrhoea (with moderate and severe dysmenorrhoea on the basis of a verbal multidimensional scoring system), were evaluated for three cycles. In the first cycle no medication was given (control cycle), in the second and third cycles (treatment cycles) received either Zintoma (250 mg q6h orally) or placebo (250 mg q6h orally) for three days, during menstrual cycles, in a design A-B or B-A. The participants recorded their menstrual pain (with a visual analogue self assessment) and evaluated 10 dysmenorrhoeic symptoms. Intensity of pain in these cycles was compared by total score. The total score was sum of the daily scores during each cycle. Statistical analyses were performed by the independent and paired t-test and repeated measurement analysis method. ResultsBoth of the drugs effectively relieved menstrual pain as compared with the control cycles (P<0.05). But the pain reduction didn&#39;t show significant difference in the two treatment (P=0.46). When comparing both treatment, Zintoma show significant different as to fatigue, anger, muscular cramp and clot drain (P<0.05). ConclusionPlacebo and Zintoma are effective in relieving pain due to primary dysmenorrhea. Also Zintoma can effect on other symptoms, so it can be used as a drug supplement. Primary dysmenorrhea,Zintoma,Ginger (Zingiber officina) 5 9 http://mcj.bums.ac.ir/browse.php?a_code=A-10-1-415&slc_lang=fa&sid=1 Marzieh Torshiz مرضیه ترشیزی 10031947532846004728 10031947532846004728 Yes Instructor; Faculty of Nursing and Midwifery, Birjand University of Medical Sciences. Birjand, Iran. Email: m3torshizi@yahoo.com کارشناس ارشد مامایی، عضو هیات علمی دانشکده پرستاری و مامایی دانشگاه علوم پزشکی بیرجند. تلفن: 9-4443041-0561 پست الکترونیک: m3torshizi@yahoo.com Nahid Golmakani ناهید گلمکانی 10031947532846004729 10031947532846004729 No Instructor; Faculty of Nursing and Midwifery, Mashhad University of Medical Sciences. Mashhad, Iran. کارشناس ارشد مامایی، عضو هیات علمی دانشکده پرستاری و مامایی دانشگاه علوم پزشکی مشهد Alireza Saadatjoo علی رضا سعادت جو 10031947532846004730 10031947532846004730 No Instructor; Faculty of Nursing and Midwifery, Birjand University of Medical Sciences. Birjand Iran. کارشناس ارشد پرستاری، عضو هیات علمی دانشکده پزشکی دانشگاه علوم پزشکی مشهد Hassan Rakhshandeh حسن رخشنده 10031947532846004731 10031947532846004731 No Pharmacia, Faculty of Medicine, Mashhad University of Medical Sciences. Mashhad, Iran. داروساز، عضو هیات علمی دانشکده پزشکی دانشگاه علوم پزشکی مشهد