en General پژوهشي Research Article <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><strong>Background:</strong> Reports indicate that probiotics have beneficial effects on both the prevention and treatment of numerous diseases.<br> <strong>Objectives: </strong>This study aims to explore the overall inclination toward probiotic consumption, its trends, and its association with common gastrointestinal diseases.<br> <strong>Methods:</strong> We conducted an ecological study utilizing Google Trends (GTs) and Global Concern data. We analyzed search terms related to &ldquo;probiotic,&quot; &ldquo;Irritable Bowel Syndrome (IBS),&quot; &ldquo;Peptic,&quot; &ldquo;Constipation,&quot; &ldquo;Diarrhea,&quot; and &ldquo;Stomach Cancer (SC)&quot; across all searches performed on GTs from January 2014 to July 2023.<br> <strong>Results: </strong>Globally and in Iran, there has been an increasing interest in consuming probiotics over time. This increase is linked to a rise in cases of stomach cancer and irritable bowel syndrome, which, in turn, boosts the propensity to utilize probiotics. Globally, there is a direct correlation between probiotic consumption and IBS (R = +0.69, P = 0.0001), peptic disorders (R = +0.71, P = 0.001), Constipation (R = +0.93, P = 0.001), and diarrhea (R = +0.89, P = 0.001). In Iran, significant direct correlations were found between probiotic consumption and both constipation (R = +0.36, P = 0.001) and diarrhea (R = +0.40, P = 0.001). Among probiotic-containing products, yogurt was preferred over others worldwide and in Iran.<br> <strong>Conclusions:</strong> The interest in probiotic use is high globally and in Iran. Consequently, there is a need for strategies to educate the public about the areas where the benefits of probiotics are well-supported by evidence and where information is either weak or lacking.</span></span></div> Probiotics,Peptic Ulcer,Constipation,Diarrhea,Irritable Bowel Syndrome 0 0 http://mcj.bums.ac.ir/browse.php?a_code=A-10-1-285&slc_lang=en&sid=1 Mohammadreza Rabiee 10031947532846005026 10031947532846005026 No Department of Sport Sciences, International Division, Shiraz University, Shiraz, Iran Masoumeh Sadat Mousavi mousavi68.ma@yahoo.com 10031947532846005027 10031947532846005027 Yes Department of Epidemiology and Biostatistics, School of Health Shahrekord University of Medical Sciences, Shahrekord, Iran