en General گزارش مورد case report <div style="text-align: justify;"><span style="font-size:14px;"><span style="font-family:Times New Roman;"><strong>Introduction:</strong>&nbsp;Coronavirus disease 2019 (COVID-19) has emerged as a pandemic and is accompanied by extraordinary morbidity and mortality. Critically ill COVID-19 patients have frequent thrombotic problems and laboratory evidence of hypercoagulability. The spectrum of presentations and complications of COVID-19 is still evolving. We describe a patient with unusual visual symptoms as the presenting signs of COVID-19.<br> <strong>Case Presentation:</strong>&nbsp;In this case report, we describe a patient who presented with acute severe bilateral visual loss and headache. On neurological examination, cranial nerves were normal. There was no motor and sensorial abnormality. While the patient was in the emergency room, he was tested positive for COVID-19 via nasopharyngeal swab polymerase chain reaction (PCR) as part of COVID-19 surveillance. An unenhanced brain CT scan showed infarction in the occipital cortex bilaterally due to ischemic stroke involving the Posterior Cerebral Artery (PCA). A few hours later, oxygen saturation was 42%, and a sudden decline of consciousness was observed, progressing to coma. The neurosurgery intervention failed to change the patient&#39;s status, and he was pronounced dead in the next few hours.<br> <strong>Conclusions:&nbsp;</strong>This case illuminates a wide range of COVID-19-related symptomatology and highlights the need for clinicians to be aware of different clinical appearances associated with this infection.</span></span></div> Ophthalmology,Stroke,Vision Loss,COVID-19 0 0 http://mcj.bums.ac.ir/browse.php?a_code=A-10-1-189&slc_lang=en&sid=1 Kazem Ghaemi 10031947532846005378 10031947532846005378 No Department of Neurosurgery, School of Medicine, Cellular and Molecular Research Center, Birjand University of Medical Sciences, Birjand, Iran Tahereh Darvishpour Kakhki 10031947532846005379 10031947532846005379 No Ophthalmologist, Department of Ophthalmology, Razi Hospital, Birjand University of Medical Sciences, Birjand, Iran Fatemeh Abbasi 10031947532846005380 10031947532846005380 No Research Committee, Birjand University of Medical Sciences, Birjand, Iran Malihe Nikandish 10031947532846005381 10031947532846005381 Yes Razi Hospital, Birjand, Iran. Email: nikandishm@bums.ac.ir