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Rabeifar F. Big Data Analytics, Machine Learning, Telemedicine, Nursing Informatics, Patient Safety, Systematic Review. Mod Care J 2026; 23 (3) :47-55
URL: http://mcj.bums.ac.ir/article-1-606-en.html
Department of Computer Engineering, ShQ.C., Islamic Azad University, Shahr-e Qods, Iran. Email: fa.rabeifar@iau.ac.ir
Abstract:   (542 Views)
Context: Telemedicine has become a central component of modern healthcare, enabling remote and accessible care delivery through digital innovations. The integration of big data analytics (BDA) and Machine learning (ML) offers significant potential to enhance nursing practice, strengthen patient safety, and improve care quality. However, the existing literature on their applications remains fragmented, underscoring the need for a comprehensive synthesis.
Objectives: This review aims to systematically examine how BDA and ML are utilized in telemedicine to support nursing practice, promote patient safety, and enhance care quality. It further identifies key challenges and outlines future directions for the ethical and sustainable integration of these technologies. Evidence Acquisition: This systematic review was conducted using English and Persian peer-reviewed articles, systematic reviews, and grey literature published between Jan 2015 and April 2025 (PRISMA).
Data Sources: The databases searched included PubMed, CINAHL, Scopus, and IEEE Xplore. Eligible studies addressed the application of BDA or ML in telemedicine concerning nursing workflows, patient safety, or care quality. Out of 623 screened records, 47 studies met inclusion criteria and were thematically analyzed.
Results: The review indicates that BDA and ML are widely applied in predictive analytics for early deterioration detection, personalized care planning, and continuous remote monitoring with automated alerts. These technologies assist nurses by optimizing workflows, reducing administrative tasks, and enhancing evidence-based decision-making. Reported benefits include fewer medication errors, timely interventions, and improved monitoring of high-risk patients. Nevertheless, barriers such as privacy and security issues, algorithmic bias, interoperability challenges, and the need for enhanced digital literacy among nurses persist.
Conclusions: The BDA and ML hold transformative potential to advance telemedicine by empowering nurses with actionable, data-driven insights that improve patient safety and care quality. Achieving sustainable integration will require interdisciplinary collaboration, ethical artificial intelligence (AI) frameworks, robust data governance, and targeted educational initiatives to ensure equitable and effective implementation. Future implementations should prioritize nurse-led AI governance and ongoing digital competency training programs.
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Article Types: Systematic Review | Subject: General
Received: 2025/09/14 | Accepted: 2026/01/5 | Published: 2026/07/14

References
1. Rabeifar F, Radfar R, Toloie Eshlaghy A. Cloud Robotic for Development of Smart Telemedicine. J Biomed Phys Eng. 2022;12(3):225-6. [PubMed ID: 35698537]; [PubMed Central ID: PMC9175123]. [DOI:10.31661/jbpe.v0i0.2202-1465]
2. Anggo S, Rahman W, Chai S, Pao C. Telemedicine in the Digital Era: Changing the Face of Health Services with Virtual Technology. J World Future Med Health Nurs. 2025;3(1):30-41. [DOI:10.70177/health.v3i1.1897]
3. Stan IE, D'Auria D, Napoletano P.A Systematic Literature Review of Innovations, Challenges, and Future Directions in Telemonitoring and Wearable Health Technologies. IEEE J Biomed Health Inform. 2025; PP. [PubMed ID: 40794502]. [DOI:10.1109/JBHI.2025.3598056]
4. Alfehaid AH, Balhareth WAM, Al-Mutairi SB, Aleissa SS, Asiri SAM, Alanazi MAM, et al. Behind the Curve: Addressing the Nursing Crisis Fueled by Limited Technological Advances in Healthcare. J Int Crisis Risk Commun Res. 2024;7(S4):30.
5. Duckett K. Telemedicine Today: Integral to Healthcare. Home Healthc Now. 2025;43(4):253-4. [PubMed ID: 40619630]. [DOI:10.1097/NHH.0000000000001363]
6. Mehedy MTJ, Jalil MS, Saeed M, Mamun AA, Snigdha EZ, Khan MDN, et al. Big Data and Machine Learning in Healthcare: A Business Intelligence Approach for Cost Optimization and Service Improvement. American J Med Sci Pharmaceut Res. 2025;7(3):115-35. [DOI:10.37547/tajmspr/Volume07Issue03-14]
7. Prawira N, Natalia F; Wella. Exploring the Role of Machine Learning and Big Data Analytics in Enhancing Decision-Making Processes: A Systematic Literature Review. Int J Inform Visual. 2025;9(4). [DOI:10.62527/joiv.9.4.3244]
8. Kumar S, Sharma D, Rao S, Lim WM, Mangla SK. Past, present, and future of sustainable finance: insights from big data analytics through machine learning of scholarly research. Ann Oper Res. 2022:1-44. [PubMed ID: 35002001]; [PubMed Central ID: PMC8723819]. [DOI:10.1007/s10479-022-04535-4]
9. Rao Chinta PC. Predictive Analytics for Disease Diagnosis: A Study on Healthcare Data with Machine Learning Algorithms and Big Data. J Cancer Sci. 2025;10(1). [DOI:10.13188/2377-9292.1000029]
10. Rabeifar F, Radfar R, Toloie Eshlaghy A. Security in Telemedicine based IoT. Health Manag Inform Sci. 2021;8(3):200-9. [DOI: 10.30476/jhmi.2022.92061.1091]
11. Javed H, El-Sappagh S, Abuhmed T. Robustness in deep learning models for medical diagnostics: security and adversarial challenges towards robust AI applications. Artific Intell Rev. 2024;58(1). [DOI:10.1007/s10462-024-11005-9]
12. Balendran A, Beji C, Bouvier F, Khalifa O, Evgeniou T, Ravaud P, et al. A scoping review of robustness concepts for machine learning in healthcare. NPJ Digit Med. 2025;8(1):38. [PubMed ID: 39824951]; [PubMed Central ID: PMC11742061]. [DOI:10.1038/s41746-024-01420-1]
13. Rabeifar F, Radfar R, Toloie Eshlaghy A. Cloud-Based Smart Telemedicine. Int J Basic Sci Med. 2022;7(3):96-7. [DOI:10.34172/ijbsm.2022.17]
14. Menagadevi M, Madian N, Thiyagarajan D, Rajendran R. Smart medical devices: making healthcare more intelligent. In: Tripathi SL, Balas VE, Mahmud M, Banerjee S, editors. Machine Learning Models and Architectures for Biomedical Signal Processing. London, UK: Academic Press; 2025. p. 487-501. [DOI:10.1016/B978-0-443-22158-3.00020-X]
15. Yang Y, Siau K, Xie W, Sun Y. Smart Health. J Organiz End User Comput. 2022;34(1):1-14. [DOI:10.4018/JOEUC.308814]
16. Manickam P, Mariappan SA, Murugesan SM, Hansda S, Kaushik A, Shinde R, et al. Artificial Intelligence (AI) and Internet of Medical Things (IoMT) Assisted Biomedical Systems for Intelligent Healthcare. Biosensors. 2022;12(8). [PubMed ID: 35892459]; [PubMed Central ID: PMC9330886]. [DOI:10.3390/bios12080562]
17. Hassan MK, El Desouky AI, Elghamrawy SM, Sarhan AM. Big Data Challenges and Opportunities in Healthcare Informatics and Smart Hospitals. In: Hassanien AE, Elhoseny M, Ahmed SH, Singh AK, editors. Security in Smart Cities: Models, Applications, and Challenges. Cham, Switzerland: Springer; 2019. p. 3-26. [DOI:10.1007/978-3-030-01560-2_1]
18. Jiwani N, Gupta K, Whig P. Machine Learning Approaches for Analysis in Smart Healthcare Informatics. In: Gupta K, Sharma SK, Hassanien AE, editors. Machine Learning and Artificial Intelligence in Healthcare Systems. Boca Raton, USA: CRC Press; 2022. p. 129-54. [DOI:10.1201/9781003265436-6]
19. Ismail Y, Seriga Gancy E. A Review of Evolution and Applications of Telemedicine in Healthcare. J Pharma Insights Res. 2025;3(2):43-52. [DOI:10.69613/nf7eh215]
20. Blhaj KMS, Dhameria V, Muazeib AIM. The Role of Telemedicine in Digital Transformation Based on Patient Perceptions of Healthcare Accessibility and Efficiency. Int J Nurs Info. 2025;4(1):10-20. [DOI:10.58418/ijni.v4i1.131]
21. Cut K, Al M, Nur F, Maulina D, Shabrina S. Telemedicine: Between Opportunities, Expectations, and Challenges in Health Development in Remote Areas of Indonesia. Int J Law Soc Sci Human. 2025;2(2):285-94. [DOI:10.70193/ijlsh.v2i2.258]
22. Alzahrani AA. A Comprehensive Review of Interoperability Challenges and Applications Beyond Cryptocurrencies. Adv Artific Intell Machine Learn. 2022;5(1):3356-72.
23. Pratap MS, Arulkumaran G. Machine Learning-Based Predictive Analytics for Health Diagnosis: A Case Study on Diabetes Prediction. 3rd International Conference on Inventive Computing and Informatics (ICICI 2025). Internet. IEEE; 2025. p. 500-5. [DOI:10.1109/ICICI65870.2025.11069448]
24. Soni N, Nigam N. Recent Advances in Artificial Intelligence and Machine Learning: Trends, Challenges, and Future Directions. Int J Engineer Trends Appl. 2025;12(1):9-12.
25. Schunke LC, Mello B, da Costa CA, Antunes RS, Rigo SJ, Ramos GO, et al. A rapid review of machine learning approaches for telemedicine in the scope of COVID-19. Artif Intell Med. 2022; 129:102312. [PubMed ID: 35659388]; [PubMed Central ID: PMC9055383]. [DOI:10.1016/j.artmed.2022.102312]
26. Zobair KM, Sanzogni L, Houghton L, Islam MZ. Forecasting care seekers satisfaction with telemedicine using machine learning and structural equation modeling. PLoS One. 2021;16(9). e0257300. [PubMed ID: 34559840]; [PubMed Central ID: PMC8462681]. [DOI:10.1371/journal.pone.0257300]
27. Christopoulou SC. Machine Learning Models and Technologies for Evidence-Based Telehealth and Smart Care: A Review. BioMedInformatics. 2024;4(1):754-79. [DOI:10.3390/biomedinformatics4010042]
28. Yadav S, Bhole GP, Sharma A. Telemedicine using Machine Learning: A Boon. Emerging Computational Approaches in Telehealth and Telemedicine: A Look at The Post COVID-19 Landscape. Landscape. 2022; 1:70. [DOI:10.2174/9789815079272122010006]
29. Rahmaty M. Machine learning with big data to solve real-world problems. J Data Analytics. 2023;2(1):9-16. [DOI:10.59615/jda.2.1.9]
30. Ray S. A Quick Review of Machine Learning Algorithms. 2019 International Conference on Machine Learning, Big Data, Cloud and Parallel Computing (COMITCon). Piscataway, USA. IEEE; 2019. p. 35-9. [DOI:10.1109/COMITCon.2019.8862451]
31. Sarker IH. Machine Learning: Algorithms, Real-World Applications and Research Directions. SN Comput Sci. 2021;2(3):160. [PubMed ID: 33778771]; [PubMed Central ID: PMC7983091]. [DOI:10.1007/s42979-021-00592-x]
32. Ferdous M, Debnath J, Chakraborty NR. Machine Learning Algorithms in Healthcare: A Literature Survey. 2020 11th International Conference on Computing, Communication and Networking Technologies (ICCCNT). Internet. IEEE; 2020. p. 1-6. [DOI:10.1109/ICCCNT49239.2020.9225642]
33. Awasthi R, Ramachandran SP, Mishra S, Mahapatra D, Arshad H, Atreja A, et al. Artificial Intelligence in Healthcare: 2024 Year in Review. MedRxiv. 2025; Preprint. [DOI:10.1101/2025.02.26.25322978]
34. Ahmed W. The Role of Machine Learning and Deep Learning in Revolutionizing Healthcare: A Review. Prem J Artific Intell. 2025; 3:100010. [DOI:10.70389/PJAI.100010]
35. Husain G, Mayer J, Bekbolatova M, Vathappallil P, Matalia M, Toma M. Machine learning for medical image classification. Acad Med. 2024;1(4). [DOI:10.20935/AcadMed7444]
36. Sadr H, Nazari M, Khodaverdian Z, Farzan R, Yousefzadeh-Chabok S, Ashoobi MT, et al. Unveiling the potential of artificial intelligence in revolutionizing disease diagnosis and prediction: a comprehensive review of machine learning and deep learning approaches. Eur J Med Res. 2025;30(1):418. [PubMed ID: 40414894]; [PubMed Central ID: PMC12105400]. [DOI:10.1186/s40001-025-02680-7]
37. Kadum SY, Salman OH, Taha ZK, Said AB, Ali MA, Qassim QS, et al. Machine learning-based telemedicine framework to prioritize remote patients with multi-chronic diseases for emergency healthcare services. Network Model Analysis Health Info Bioinfo. 2023;12(1). [DOI:10.1007/s13721-022-00407-w]
38. Rashid MM. A Machine Learning Approach to Predicting Users' Intention to Adopt Telemedicine in Healthcare. J Sci Technol Res. 2025;6(1):30-7. [DOI:10.59738/jstr.v6i1.24(30-37).famf2507]
39. Jamal A. Effect of Telemedicine Use on Medical Spending and Health Care Utilization: A Machine Learning Approach. AJPM Focus. 2023;2(3):100127. [PubMed ID: 37790663]; [PubMed Central ID: PMC10546505]. [DOI:10.1016/j.focus.2023.100127]
40. Prabowo A. The Future of Digital Health: Integrating AI, Big Data, and Telemedicine in Global Healthcare. Proceed Int Conference Innov Sci Technol Educ Children Health. 2025;5(1):146-57. [DOI:10.62951/icistech.v5i1.276]
41. Wang B, Shi X, Han X, Xiao G. The digital transformation of nursing practice: an analysis of advanced IoT technologies and smart nursing systems. Front Med. 2024; 11:1471527. [PubMed ID: 39678028]; [PubMed Central ID: PMC11638746]. [DOI:10.3389/fmed.2024.1471527]
42. Bairagi VK. Big Data Analytics in Telemedicine: A Role of Medical Image Compression. In: García Márquez FPLB, editor. Big Data Management. Cham, Switzerland: Springer International Publishing; 2017. p. 123-60. [DOI:10.1007/978-3-319-45498-6_7]
43. Pasipoularides A. COVID-19, Big Data: how it will change the way we practice Medicine. QJM. 2021;114(5):293-5. [PubMed ID: 33151333]; [PubMed Central ID: PMC7665728]. [DOI:10.1093/qjmed/hcaa299]
44. Gezimati M, Singh G. Forecasting Healthcare 5.0 Driven IoMT for a Seamless Continuum of Care. IEEE Access. 2025; 13:118163-84. [DOI:10.1109/ACCESS.2025.3583884]
45. Jalali MS, Landman A, Gordon WJ. Telemedicine, privacy, and information security in the age of COVID-19. J Am Med Inform Assoc. 2021;28(3):671-2. [PubMed ID: 33325533]; [PubMed Central ID: PMC7798938]. [DOI:10.1093/jamia/ocaa310]
46. Pramesha Chandrasiri GA, Halgamuge MN, Subhashi Jayasekara C. A Comparative Study in the Application of IoT in Health Care: Data Security in Telemedicine. In: Mahmood Z, editor. Security, Privacy and Trust in the IoT Environment. Cham, Switzerland: Springer International Publishing; 2019. p. 181-202. [DOI:10.1007/978-3-030-18075-1_9]
47. Kanse R, Rathod V, Motekar H, Kamble P, Chavan V, Bankar J. Big data analysis for remote diagnostics in telemedicine. Artificial Intelligence and Information Technologies. Boca Raton, USA: CRC Press; 2024. p. 194-8. [DOI:10.1201/9781003510833-32]
48. Chern CC, Chen YJ, Hsiao B. Decision tree-based classifier in providing telehealth service. BMC Med Inform Decis Mak. 2019;19(1):104. [PubMed ID: 31146749]; [PubMed Central ID: PMC6543775]. [DOI:10.1186/s12911-019-0825-9]
49. R KD, P S. Optimizing Telemedicine Services for Rural Women: A Decision Tree-Based Heap Optimizer Approach for Predictive Healthcare Delivery. 2025 International Conference on Automation and Computation (AUTOCOM). Piscataway, USA. IEEE; 2025. p. 1173-8. [DOI:10.1109/AUTOCOM64127.2025.10957341]
50. Subramanian SP, Wang Y. Application of Computational Technology in Telehealth and Telesurgery. In: Wang Y, Yu T, Wang K, editors. Advanced Manufacturing and Automation XIV. Singapore, Singapore: Springer Nature; 2025. p. 416-20. [DOI:10.1007/978-981-96-2625-0_54]
51. Shaharia F, Kanis F, Md Rakib M, Md Refadul H, Md Musa A. Transforming telehealth with Artificial Intelligence: Predictive and diagnostic advances in remote patient care. World J Adv Engin Technol Sci. 2025;16(1):355-65. [DOI:10.30574/wjaets.2025.16.1.1216]
52. Kokulavani K, Manthena KV, Sakthisaravanan B, Sreelatha T, Visumathi J, Guruprakash KS, et al. Optimizing Telemedicine Patient Care with Machine Learning for Disease Progression and Treatment Planning. Engin Technol Appl Sci Res. 2025;15(4):25783-8. [DOI:10.48084/etasr.11060]
53. Samaddar S, Maiti AB, Mondal B, Bar N, Das SK. A Study Using Support Vector Machine as a Tool for Patient's Satisfaction for SARS-CoV-2 Cases Using Telemedicine. AI to Improve e-Governance and Eminence of Life. Singapore, Singapore: Springer Nature; 2023. p. 25-36. [DOI:10.1007/978-981-99-4677-8_2]
54. Uzochukwu CV, Adetiloye OA, Adedayo AO, Iwendi C. Comparative Analysis on the Use of Teleconsultation Using Support. In: Iwendi C, Boulouard Z, Kryvinska N, editors. Proceedings of ICACTCE'23 - The International Conference on Advances in Communication Technology and Computer Engineering. Cham, Switzerland: Springer Nature; 2023. p. 507-18. [DOI:10.1007/978-3-031-37164-6_37]
55. Ponnusamy V, Manickam N, Zdravković N, Simjanovic D. Advancements of Telemedicine Using Blockchain and Deep Learning for Smart Healthcare. In: Chatterjee JM, Sujatha R, Shailendra K, editors. Role of Artificial Intelligence, Telehealth, and Telemedicine in Medical Virology. Singapore, Singapore: Springer; 2024. p. 129-47. [DOI:10.1007/978-981-97-2938-8_6]
56. Tasmurzayev N, Amangeldy B, Imanbek B, Baigarayeva Z, Imankulov T, Dikhanbayeva G, et al. Digital Cardiovascular Twins, AI Agents, and Sensor Data: A Narrative Review from System Architecture to Proactive Heart Health. Sensors. 2025;25(17). [PubMed ID: 40942702]; [PubMed Central ID: PMC12431230]. [DOI:10.3390/s25175272]
57. Rabeifar F. WSN Technologies in Designing a Telemedicine Network. J Biomed Phys Eng. 2025;15(2). [DOI:10.31661/jbpe.v0i0.2411-1852]
58. Ahmad MK, Abir MA, Akter F, Hasan T, Shaha P, Hossain MM, et al. A Secure Telemedicine Scheme Based on Distributed Database, Machine Learning and Iot for Diagnosis of Diabetes Disease. Machine Learn Iot Diagnos Diabetes Dis. 2025. [DOI:10.2139/ssrn.5205532]
59. Elaziz B, Zaouiat CEA, Eddabbah M, Laaziz Y. Enhancing SVM and KNN Performance Through Preprocessing Pipelines for Interactive mHealth Applications. Int J Adv Comput Sci Appl. 2025;16(6). [DOI:10.14569/IJACSA.2025.0160665]
60. Borkakoty S, Islam AU, Bora KC. Improving Remote Patient Monitoring and Care Using Machine Learning. In: Singh P, Kumar CJ, editors. Revolutionizing Healthcare: Impact of Artificial Intelligence on Diagnosis, Treatment, and Patient Care. Cham, Switzerland: Springer Nature; 2025. p. 179-93. [DOI:10.1007/978-3-031-80813-5_11]
61. Muhsen DK, Khmas BF, Ahmed AA, Sadiq AT. Comparative Analysis of Machine Learning Models for Predictive Healthcare in Chronic Disease Management. J Intell Syst Internet Things. 2025;17(2). [DOI:10.54216/JISIoT.170204]
62. Ambati SS. Cloud-Based Environment for Healthcare Data Management: Implementation, Benefits, and Challenges. Int J Sci Technol. 2025;16(1). [DOI:10.71097/IJSAT.v16.i1.2802]
63. Venkat MS. The Evolution of Electronic Health Records in India: Progress, Challenges, and Future Prospects (2020-2025). Int J Health Technol Innov. 2025;4(2):24-30. [DOI:10.60142/ijhti.v4i02.06]
64. Bacha A, Khan Sherani AM. AI in Predictive Healthcare Analytics: Forecasting Disease Outbreaks and Patient Outcomes. Global Trends Sci Technol. 2025;1(1):1-14. [DOI:10.70445/gtst.1.1.2025.1-14]
65. Mishkin AD, Zabinski JS, Holt G, Appelbaum PS. Ensuring privacy in telemedicine: Ethical and clinical challenges. J Telemed Telecare. 2023;29(3):217-21. [PubMed ID: 36349356]. [DOI:10.1177/1357633X221134952]

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