fa گزارش دو مورد از تب خونریزی‌دهنده کریمه و کنگو و یک مورد مشکوک در خراسان جنوبی در سال 1390 General پژوهشي Research Article Crimean–Congo hemorrhagic fever (CCHF) is a zoonotic viral hemorrhagic disease, which can be seen in Asia, Africa, East Europe and the Middle East. Mortality rate of this disease is about 30% which can be reduced with timely diagnosis and treatment with Ribavirin and supportive care. In this paper, two confirmed and one suspected cases of CCHF are introduced. Three days after the death of a woman with Disseminated Intravascular Coagulation (DIC) in the infectious diseases ward, a nurse working there and a housewife living in the city of Birjand, had been referred with vaginal bleeding. With suspicious to CCHF, both of them underwent oral treatment with Ribavirin and broad-spectrum antibiotics. The first case had expired in ICU before performing CCHF diagnostic tests but in the latter two cases the disease was confirmed through molecular tests. The nurse refused to hospitalize and used self-medication at home. However, five days after the symptoms started, she referred to the hospital with a bad general health status, vaginal bleeding and low consciousness and eventually died of this disease. But the second patient recovered after receiving a dose of drug and supportive measures and discharged with a good general health status. Contraceptive Devices Female,Intrauterine Devices,Side effects 174 178 http://mcj.bums.ac.ir/browse.php?a_code=A-10-1-580&slc_lang=fa&sid=1 Masood ziaee مسعود ضیائی 10031947532846004349 10031947532846004349 Yes Associate Professor, Department of Internal Medicine, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran. Email: dr.m.ziaee@gmail.com دانشیار گروه آموزشی داخلی- عفونی دانشکده پزشکی و عضو مرکز تحقیقات بیماریهای عفونی دانشگاه علوم پزشکی بیرجند، ایران. تلفن: 0561443002 پست الکترونیک: dr.m.ziaee@gmail.com Ghodsiyeh Azarkar قدسیه آذرکار 10031947532846004350 10031947532846004350 No Resident of Radiology, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran دستیار تخصصی رادیولوژی، دانشکده پزشکی، دانشگاه علوم پزشکی مشهد، ایران Majid Shayesteh مجید شایسته 10031947532846004351 10031947532846004351 No Physician, Birjand University of Medical Sciences, Birjand, Iran پزشک عمومی، مرکز بهداشت استان خراسان جنوبی، دانشگاه علوم پزشکی بیرجند، ایران