fa شیوع چاقی و توزیع چربی بدن در بیماران با انفارکتوس قلبی زودرس General پژوهشي Research Article Background and Aim: Obesity is a major modifiable risk factor for coronary artery disease, but its relationship with acute myocardial infarction (AMI) in early age is poorly documented. In this study we evaluated the prevalence of obesity in premature AMI.   Materials and Methods: In this case-control study we assess 94 consecutive patients with AMI before the age of 50 years and 94 age-and sex- matched neighborhood healthy controls without a history of cardiovascular disease. Definition of obesity based on the body mass index (BMI> 30).   BMI was calculated as weight in kg divided by height in square meters. Waist circumference was measured at the horizontal level of the umbilicus and WHR was a ratio of waist circumference to hip circumference measured at the horizontal level of the maximal protrusion of the gluteal muscles. Data collected and entered to SPSS and analysed by t-test and chi-square.   Results: The mean of BMI and waist to hip ratio (WHR) was significantly higher in case groups [BMI (27.1±4.4 in case and 25.7±4.4 in control group P= 0.04), WHR (0.93±0.07 in case and 0.91±0.06 in control group P= 0.01)]. Prevalence of obesity (BMI ≥ 30) is higher in case groups (27.7% in case, 14% in control P=0.021, OR= 2.35, CI%95= 1.12- 4.93 ).   Conclusion: In this case-control population-based study, obesity and higher WHR are independently associated with the premature AMI. Obesity,WHR,Waist circumference,Hip circumference,AMI,Abdominal obesity 5 10 http://mcj.bums.ac.ir/browse.php?a_code=A-10-1-579&slc_lang=fa&sid=1 Toba Kazemi طوبی کاظمی 10031947532846004444 10031947532846004444 Yes Associate Professor, Department of Cardiology, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran. Email: med_847@yahoo.com دانشیار گروه آموزشی قلب و عروق، دانشکه پزشکی و عضو مرکز تحقیقات قلب دانشگاه علوم پزشکی بیرجند، ایران. تلفن: 0561- 443004 پست الکترونیک: med_847@yahoo.com Gholamreza Sharifzadeh غلامرضا شریف‌زاده 10031947532846004445 10031947532846004445 No Instructor, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran کارشناسی ارشد اپیدمیولوژی، عضو هیات علمی دانشکده پزشکی دانشگاه علوم پزشکی بیرجند Asghar Zarban اصغر زربان 10031947532846004446 10031947532846004446 No Associate Professor, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran دانشیار گروه آموزشی علوم آزمایشگاهی دانشکده پزشکی، دانشکده علوم پزشکی بیرجند Azita Fesharakinia آزیتا فشارکی‌نیا 10031947532846004447 10031947532846004447 No Associate Professor, Department of Pediatrics, Faculty of Medicine, Birjand University of Medical Sciences, Birjand, Iran دانشیار گروه آموزشی کودکان، دانشکده پزشکی، دانشگاه علوم پزشکی بیرجند